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Article

Migration Phenotype of Brain-Cancer Cells Predicts Patient Outcomes.

Cell reports - 21 Jun 2016

Smith Chris L, Kilic Onur, Schiapparelli Paula, Guerrero-Cazares Hugo, Kim Deok-Ho, Sedora-Roman Neda I, Gupta Saksham, O'Donnell Thomas, Chaichana Kaisorn L, Rodriguez Fausto J, Abbadi Sara, Park JinSeok, Quiñones-Hinojosa Alfredo, Levchenko Andre

Abstract excerpt

Glioblastoma multiforme is a heterogeneous and infiltrative cancer with dismal prognosis. Studying the migratory behavior of tumor-derived cell populations can be informative, but it places a high premium on the precision of in vitro methods and the relevance of in vivo conditions. In particular, the analysis of 2D cell migration may not reflect invasion into 3D extracellular matrices in vivo. Here, we describe a...

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Identifiers

PMID: 27292647
DOI: 10.1016/j.celrep.2016.05.042
PMCID: PMC5517094

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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