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The Enteric Microbiome in Early-Onset Colorectal Cancer: A Comprehensive Review of Its Role as a Biomarker of Disease

28 May 2025

Abstract excerpt

Early-onset colorectal cancer (EoCRC), a distinct entity from late-onset colorectal cancer (LoCRC), continues to increase in incidence. Known risk factors for LoCRC have been explored to explain this trend, but do not account for it completely. The gastrointestinal microbiome has been associated with LoCRC and additional risk factors of disease; however, it is only now being investigated in the context of EoCRC....

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PMID: 40434363
DOI: 10.14309/ctg.0000000000000864

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