Article
Rising incidence of early-onset colorectal cancer - a call to action.
Nature reviews. Clinical oncology - 1 Apr 2021
Akimoto Naohiko, Ugai Tomotaka, Zhong Rong, Hamada Tsuyoshi, Fujiyoshi Kenji, Giannakis Marios, Wu Kana, Cao Yin, Ng Kimmie, Ogino Shuji
Abstract excerpt
The incidence of early-onset colorectal cancer (CRC), which occurs in individuals <50 years of age, has been increasing worldwide and particularly in high-income countries. The reasons for this increase remain unknown but plausible hypotheses include greater exposure to potential risk factors, such as a Western-style diet, obesity, physical inactivity and antibiotic use, especially during the early prenatal to...
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