Consistent signatures in the human gut microbiome of old- and young-onset colorectal cancer

Abstract excerpt

The incidence of young-onset colorectal cancer (yCRC) has been increasing in recent decades, but little is known about the gut microbiome of these patients. Most studies have focused on old-onset CRC (oCRC), and it remains unclear whether CRC signatures derived from old patients are valid in young patients. To address this, we assembled the largest yCRC gut metagenomes to date from two independent cohorts and...

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• Colorectal Cancer Screening and Detection
• Gut microbiota and health
• Mycobacterium research and diagnosis