Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The risk of a second primary cancer in PTEN Hamartoma Tumor Syndrome (PHTS)

24 May 2025

Abstract excerpt

PURPOSE: Patients with PTEN Hamartoma Tumor Syndrome (PHTS) have high hereditary cancer risks for breast, endometrial, and thyroid cancer. Patients develop multiple primary cancers, but these risks remain uncertain. We aimed to provide the second primary cancer risk. METHODS: This European cohort study assessed second primary cancer risks with Kaplan-Meier analyses using data from medical files, registries and/or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA gene mutations in cancer
Share to Cancer Diagnosis and Treatment
Share to Multiple and Secondary Primary Cancers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40433764
DOI: 10.1016/j.gim.2025.101467

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The risk of a second primary cancer in PTEN Hamartoma Tumor Syndrome (PHTS)PMID 40433764Read ↗

Cancer risks by sex and variant type in PTEN hamartoma tumor syndromeSemantic proximity Read ↗

A review on age‐related cancer risks in PTEN hamartoma tumor syndromeSemantic proximity Read ↗

Extended spectrum of cancers in PTEN hamartoma tumor syndromeSemantic proximity Read ↗

Histopathological phenotyping of cancers in PTEN Hamartoma Tumor Syndrome for improved recognition: A single-center study.Semantic proximity Read ↗

High cumulative risks of cancer in patients with <i>PTEN</i> hamartoma tumour syndromeSemantic proximity Read ↗

Breast cancer risk and clinical implications for germline PTEN mutation carriers.Semantic proximity Read ↗

Longitudinal Analysis of Cancer Risk in Children and Adults With Germline PTEN Variants.Semantic proximity Read ↗

Deep Phenotyping of Pathology-Confirmed Benign Lesions in PTEN Hamartoma Tumor Syndrome Patients.Semantic proximity Read ↗

PTEN hamartoma tumour syndrome: what happens when there is no PTEN germline mutation?Semantic proximity Read ↗

Second malignant neoplasms in patients with Cowden syndrome with underlying germline PTEN mutations.Semantic proximity Read ↗

Integrated Clinicogenomic Risk Modeling for Metachronous Second Primary CancersSemantic proximity Read ↗

PTEN hamartoma tumor syndromes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.