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An Overview of Oxidative Stress in Sex Chromosome Aneuploidies in Pediatric Populations

29 Apr 2025

Abstract excerpt

BACKGROUND: Oxidative stress, defined as an imbalance between reactive oxygen species and antioxidant defenses, plays a pivotal role in the pathogenesis of sex chromosome aneuploidies (SCAs), such as Turner syndrome (TS) and Klinefelter syndrome (KS). Pediatric patients with SCAs are particularly susceptible due to hormonal deficiencies, metabolic disturbances, and systemic complications. METHODS: A comprehensive...

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Share to Chromosomal and Genetic Variations
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PMID: 40427413
DOI: 10.3390/antiox14050531

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