Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

From Klinefelter Syndrome to High Grade Aneuploidies: Expanding the Gene-dosage Effect of Supernumerary X Chromosomes

9 Jan 2024

Abstract excerpt

OBJECTIVE: High-grade aneuploidies of X and Y sex chromosomes (HGAs) are exceedingly rare and complex conditions. We aimed to investigate the effect of supernumerary X chromosomes (extra-Xs) on the clinical, hormonal, metabolic, and echocardiographic features of patients with HGAs. DESIGN AND METHODS: In a cross-sectional study, we compared 23 subjects with HGAs and 46 age-matched subjects with 47,XXY Klinefelter...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Sexual Differentiation and Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Thyroid Disorders and Treatments

Source

Identifiers

PMID: 38193351
DOI: 10.1210/clinem/dgad730

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

From Klinefelter Syndrome to High Grade Aneuploidies: Expanding the Gene-dosage Effect of Supernumerary X ChromosomesPMID 38193351Read ↗

Klinefelter syndrome and other sex chromosomal aneuploidiesSemantic proximity Read ↗

47,XXY Klinefelter syndrome: clinical characteristics and age-specific recommendations for medical management.Semantic proximity Read ↗

48,XXYY, 48,XXXY and 49,XXXXY syndromes: not just variants of Klinefelter syndrome.Semantic proximity Read ↗

Chromosomal Variants in Klinefelter SyndromeSemantic proximity Read ↗

Endocrine and metabolic evaluation of classic Klinefelter syndrome and high-grade aneuploidies of sexual chromosomes with male phenotype: are they different clinical conditions?Semantic proximity Read ↗

Gonadal dysfunction and beyond: Clinical challenges in children, adolescents, and adults with 47,<scp>XXY</scp> Klinefelter syndromeSemantic proximity Read ↗

Update On The Clinical Perspectives And Care Of The Child With 47,XXY (Klinefelter Syndrome)Semantic proximity Read ↗

Klinefelter syndrome: etiology and clinical considerations in male infertilitySemantic proximity Read ↗

New Horizons in Klinefelter Syndrome: Current Evidence, Gaps, and Research PrioritiesSemantic proximity Read ↗

Rare sex chromosome variation 48, XXYY : An integrative reviewSemantic proximity Read ↗

49, XXXYY: Parental Origin, Occurrence, and Clinical Phenotypes.Semantic proximity Read ↗

Prevalence, Morbidity, and Mortality of 1,609 Men with Sex Chromosome Aneuploidy: Results from the Diverse Million Veteran Program CohortSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.