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Article

Exploring the interplay of genetic variants and environmental factors in childhood obesity: A systematic review and meta-analysis.

Metabolism: clinical and experimental - 1 Sept 2025

Zhu Haoxue, Yi Xinghao, He Mengyu, Wu Siyi, Li Ming, Gao Shan

Abstract excerpt

Dynamic interactions between genetic predispositions and environmental exposures significantly shape the escalating prevalence of childhood obesity. This systematic review synthesizes observational and clinical trial evidence on the gene-environment interplays influencing childhood obesity, highlighting the role of genetic variants and environmental moderators such as dietary habits, physical activity, sleep...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 40412510
DOI: 10.1016/j.metabol.2025.156303

Genes

FTO
MC4R

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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