Evaluation of CRP SNV rs2808630 and acute proinflammatory biomarkers in patients with CKD and PLHIV with CKD: a case-control study.

doi:10.1186/s12882-025-04138-8

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Evaluation of CRP SNV rs2808630 and acute proinflammatory biomarkers in patients with CKD and PLHIV with CKD: a case-control study.

BMC nephrology - 14 May 2025

Torres-Rojas Andrea, González-Hernández Luz Alicia, Sánchez-Reyes Karina, Chávez-Iñiguez Jonathan Samuel, Topete-Reyes Jorge Fernando, Andrade-Villanueva Jaime Federico, Martínez-Ayala Pedro, Valle-Rodriguez Adriana, Ruiz-Herrera Vida Verónica, Hernández-Bello Jorge, Reyes-Castillo Zyanya, Álvarez-Zavala Monserrat

Abstract excerpt

BACKGROUND: The CKD in PLHIV is highly prevalent in Jalisco. Despite its control with ART, HIV is characterized by generating low-grade inflammation events that contribute to the development and progression of CKD. Considering the importance of hs-CRP in the context of CKD, various genetic predisposition studies have been conducted to search for variants of the CRP gene, among which the SNV rs2808630 has been...

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PMID: 40369487
DOI: 10.1186/s12882-025-04138-8
PMCID: PMC12080035

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