Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enhanced B cell and complement cascade gene signatures in patients with neuropsychiatric systemic lupus erythematosus

9 May 2025

Abstract excerpt

OBJECTIVES: The management of neuropsychiatric systemic lupus erythematosus (NPSLE) remains challenging because of clinical heterogeneity and the complexity of pathophysiologic mechanisms involved. We sought to determine the molecular signature of NPSLE and its endotypes towards novel biomarkers and targeted therapies. METHODS: Whole-blood RNA sequencing from 308 patients with systemic lupus erythematosus (119...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Monoclonal and Polyclonal Antibodies Research
Share to Multiple Sclerosis Research Studies
Share to Systemic Lupus Erythematosus Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40348638
DOI: 10.1016/j.ard.2025.04.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enhanced B cell and complement cascade gene signatures in patients with neuropsychiatric systemic lupus erythematosusPMID 40348638Read ↗

Unsupervised clustering of clinical and laboratory features of systemic lupus erythematosus: insights from a multicentre cohort.Semantic proximity Read ↗

Unveiling the clinical and genetic impact of neuropsychiatric involvement in systemic lupus erythematosus.Semantic proximity Read ↗

From Genes to Pathways: The Molecular Landscape of Systemic Lupus Erythematosus.Semantic proximity Read ↗

Comparative proteomics analysis of plasma protein in patients with neuropsychiatric systemic lupus erythematosusSemantic proximity Read ↗

Distinct gene dysregulation patterns herald precision medicine potentiality in systemic lupus erythematosusSemantic proximity Read ↗

Transcriptomic analysis reveals immune signatures associated with specific cutaneous manifestations of lupus in systemic lupus erythematosusSemantic proximity Read ↗

SLE-Diseaseome: A Comprehensive Meta-Database of Systemic Lupus Erythematosus Relevant Functional PathwaysSemantic proximity Read ↗

Signalling networks constructed by integrative analysis of multi-omics in peripheral blood mononuclear cells in systemic lupus erythematous patientsSemantic proximity Read ↗

Genomic dissection of Systemic Lupus Erythematosus: Distinct Susceptibility, Activity and Severity SignaturesSemantic proximity Read ↗

Novel CSF biomarkers for diagnosis and integrated analysis of neuropsychiatric systemic lupus erythematosus: based on antibody profilingSemantic proximity Read ↗

Integrated, multicohort analysis reveals unified signature of systemic lupus erythematosusSemantic proximity Read ↗

Update on the pathogenesis and treatment of childhood-onset systemic lupus erythematosus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.