A Principled Framework for Mendelian Randomization in Oral Health Research

Abstract excerpt

In recent years, the popularity of Mendelian randomization (MR) as a technique to investigate causal relationships has grown exponentially. This approach leverages randomness inherent in the allocation of genetic variants to circumvent issues of unobserved confounding and reverse causation that compromise many causal claims based on observational data. In this manuscript, the key assumptions required for MR...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genetic Associations and Epidemiology
• Share to Genomics and Rare Diseases
• Share to Helicobacter pylori-related gastroenterology studies