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Article

Physical Resilience May Offset Mortality Risks Associated With Genetic Predisposition to Shorter Survival: A Population-based Cohort Study.

The journals of gerontology. Series A, Biological sciences and medical sciences - 10 Jun 2025

Stark Lea, Triolo Federico, Vetrano Davide Liborio, Rizzuto Debora, Contador Israel, Calderón-Larrañaga Amaia, Dekhtyar Serhiy

Abstract excerpt

BACKGROUND: Physical resilience (PR), the ability to recover from health adversities, is thought to buffer health challenges during aging. However, PR's association with mortality and its ability to offset the negative effects of genetic susceptibility to shorter lifespan remains unknown. METHODS: Data on 3 041 individuals (age: 60+) from the Swedish National Study on Aging and Care in Kungsholmen (SNAC-K) were...

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Aged, 80 and over
Cohort Studies
Longevity
Mitochondrial Precursor Protein Import Complex Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Proportional Hazards Models

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Open in PubMed Open full text

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PMID: 40341863
DOI: 10.1093/gerona/glaf101
PMCID: PMC12202038

Genes

APOE
TOMM40

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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