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Article

Genetic etiology and clinical features of non-syndromic pediatric obesity in the Chinese population: a large cohort study.

BMC pediatrics - 7 May 2025

Hui Huang, Yu Yang, Yiwei Liang, Li Yang, Liling Xie, Dongguang Zhang

Abstract excerpt

BACKGROUND: This study aimed to investigate the genetic etiology and clinical features of non-syndromic pediatric obesity in a large Chinese cohort, providing insights into the genetic profile and its correlation with clinical phenotypes. METHODS: We enrolled 391 children, aged 7-14 years, diagnosed with non-syndromic pediatric obesity at Jiangxi Provincial Children's Hospital from January 2020 to June 2022....

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Child
China
Cohort Studies
East Asian People
Exome Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pediatric Obesity

Receptor, Melanocortin, Type 4

Uncoupling Protein 3

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Identifiers

PMID: 40329189
DOI: 10.1186/s12887-025-05702-9
PMCID: PMC12057247

Genes

MC4R
UCP3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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