Article
Investigation of the MC1R Gene Sequence Variation Using Oxford Nanopore Sequencing.
Electrophoresis - 1 Jun 2025
Branicki Wojciech, Pisarek-Pacek Aleksandra, Marszałek Kamila, Jarosz Agata, Kukla-Bartoszek Magdalena, Zubańska Magdalena, Bronikowska Agnieszka, Węgrzyn Katarzyna, Wysocka Bożena, Spólnicka Magdalena, Pośpiech Ewelina
Abstract excerpt
The MC1R gene, which is responsible for most cases of red hair, affects other hair and skin colours and contributes to differences in pain sensitivity and consists of a single exon with a very high level of allelic heterogeneity. In this research, we show that the Oxford Nanopore Technology (ONT) offers a good alternative to study the MC1R sequence variation. MinION was used to sequence the 1590 bp MC1R exon and...
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