Article
Correlation of METTL4 genetic variants and severe pneumonia pediatric patients in Southern China.
BMC genomic data - 1 May 2025
Ma Liuheyi, Zuo Xiaoyu, Lu Bingtai, Zhang Yuxia
Abstract excerpt
BACKGROUND: Pneumonia is a major cause of mortality and health burden in children under five, yet its genetic etiology remains poorly understood. Methyltransferase 4, N6-adenosine (METTL4), is a methyltransferase enzyme responsible for RNA and DNA methylation and is known to be activated under hypoxic conditions. However, its potential link to susceptibility to pneumonia has not been evaluated. This study aimed...
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