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Article

DNA methylation signatures of severe RSV infection in infants: evidence from non-invasive saliva samples

28 Apr 2025

Abstract excerpt

BACKGROUND: Respiratory syncytial virus (RSV) poses significant morbidity and mortality risks in childhood, particularly for previously healthy infants admitted to hospitals lacking predisposing risk factors for severe disease. This study aimed to investigate the role of the host epigenome in RSV infection severity using non-invasive buccal swabs from sixteen hospitalized infants admitted to the hospital for RSV...

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PMID: 40296166
DOI: 10.1186/s13072-025-00587-5

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