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Article

Association between telomere length and psychiatric disorders: a bidirectional Mendelian randomization study.

European archives of psychiatry and clinical neuroscience - 1 Jun 2026

Zhang Han, Zhou Jing, Cao Yuan, Zhang Xiaoan, Chang Hui, Zhao Yan, Bo Yacong, Zhang Huanhuan, Yu Zengli, Zhao Xin

Abstract excerpt

Observational studies have suggested that shorter telomere length (TL) may be a risk factor for psychiatric disorders. However, whether this association underlie causal effects remains unknown. This study aims to investigate the potential association between TL and psychiatric disorders by conducting a bidirectional Mendelian randomization (MR) study. Summary statistics for TL were obtained from the UK Biobank...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40278882
DOI: 10.1007/s00406-025-02008-w

Genes

PGC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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