Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel variant of telomerase reverse transcriptase (TERT) associated with risk of glioma in a Korean population.

Scientific reports - 24 Apr 2025

Lim Ho Yeon, Cheong Hyun Sub, Namgoong Seok, Chang Jong Hee, Kim Lyoung Hyo, Shin Hyoung Doo

Abstract excerpt

Among central nervous system (CNS) tumors, gliomas are the most prevalent type of tumor. Single nucleotide polymorphisms (SNPs) in telomerase reverse transcriptase (TERT) gene have been identified as risk loci for gliomas by previous genome-wide association studies (GWAS). We examined association between TERT variants and glioma risk in a Korean population. For a case-control study, a total of 32 TERT SNPs from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Brain Neoplasms
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to East Asian People

Share to Glioma

Share to Republic of Korea

Share to Risk Factors

Share to Telomerase

Source

Open in PubMed Open full text

Identifiers

PMID: 40274858
DOI: 10.1038/s41598-025-96929-0
PMCID: PMC12022312

Genes

TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel variant of telomerase reverse transcriptase (TERT) associated with risk of glioma in a Korean population.PMID 40274858Read ↗

Association of Telomerase Reverse Transcriptase Promoter Mutations with the Prognosis of Glioma Patients: a Meta-Analysis.Semantic proximity Read ↗

Association between telomerase reverse transcriptase rs2736100 polymorphism and risk of glioma.Semantic proximity Read ↗

TERT mutation in glioma: Frequency, prognosis and risk.Semantic proximity Read ↗

Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk.Semantic proximity Read ↗

TERT Genetic Mutations as Prognostic Marker in Glioma.Semantic proximity Read ↗

Genetic variant near TERC influencing the risk of gliomas with older age at diagnosis in a Chinese population.Semantic proximity Read ↗

RTEL1 and TERT polymorphisms are associated with astrocytoma risk in the Chinese Han population.Semantic proximity Read ↗

Paradoxical prognostic impact of TERT promoter mutations in gliomas depends on different histological and genetic backgrounds.Semantic proximity Read ↗

Upregulating mutations in the TERT promoter commonly occur in adult malignant gliomas and are strongly associated with total 1p19q loss.Semantic proximity Read ↗

Establishment and Validation of the Detection of TERT Promoter Mutations by Human Gliomas U251 Cell Lines.Semantic proximity Read ↗

TERT promoter mutation and its interaction with IDH mutations in glioma: Combined TERT promoter and IDH mutations stratifies lower-grade glioma into distinct survival subgroups-A meta-analysis of aggregate data.Semantic proximity Read ↗

TERT rs2853676 polymorphisms correlate with glioma prognosis in Chinese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.