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Genetic and phenotypic stability of Lacticaseibacillus paracasei DG (DSM 34154) over 10 years of industrial production

24 Apr 2025

Abstract excerpt

ABSTRACT The commercialization of a probiotic microorganism requires genetic and phenotypic consistency across production lots. However, the large-scale industrial production of probiotic microbial biomasses over years poses a risk of genetic drift, potentially affecting the probiotic’s ability to confer health benefits. This study assessed the stability of Lacticaseibacillus paracasei DG (DSM 34154), a...

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PMID: 40272178
DOI: 10.1128/aem.02394-24

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