Article
Association between Apo B, LDL-R and PCSK9 gene polymorphisms with coronary artery diseases in Egyptians.
Molecular biology reports - 14 Jun 2024
Mahsoub Nancy, Almenshawy Ahmed, Taki Eldin Ahmed Mohammad, Abdel Hay Nehal M, Youssef Amany R, El-Farahaty Reham M, El-Sayed Kefaya, Osman Adel Mohamad, Elhennawy Eman S
Abstract excerpt
BACKGROUND: Many studies have focused on the significance of lipid regulatory genes in the pathophysiology of Coronary artery disease (CAD). ApoB XbaI (rs693) and EcoRI (rs1042031) single nucleoid polymorphisms (SNPs) were investigated to detect whether they are risk factors for CAD. Till now, this association remains uncertain. SMARCA4 (rs1122608) SNP has directly related to dyslipidemia. Loss of function...
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