Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic and clinical characteristics of primary hemophagocytic lymphohistiocytosis in children.

Annals of hematology - 1 Jan 2024

Zhao Chenzi, Zhang Qing, Zhang Rui, Lian Hongyun, Ma Honghao, Zhao Xiaoxi, Li Zhigang

Abstract excerpt

To analyze the genetic variation and prognosis of primary hemophagocytic lymphohistiocytosis (pHLH) in children and the clinical features of isolated central nervous system HLH (CNS-HLH). We retrospectively analyzed the clinical and genetic data of 480 HLH children admitted to our hospital from September 2017 to September 2022. There were 66 patients (13.75%) with pHLH, and the median age was 3.21 years...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child
Share to Child, Preschool
Share to Hematopoietic Stem Cell Transplantation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lymphohistiocytosis, Hemophagocytic

Share to Membrane Proteins

Share to Mutation

Share to Prognosis

Source

Identifiers

PMID: 37851074
DOI: 10.1007/s00277-023-05499-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic and clinical characteristics of primary hemophagocytic lymphohistiocytosis in children.PMID 37851074Read ↗

Prognostic Features of Pediatric Primary Hemophagocytic Lymphohistiocytosis With CNS Involvement.Semantic proximity Read ↗

[Clinical and genetic mutation characteristics of patients with primary hemophagocytic lymphohistiocytosis and their impact on prognosis].Semantic proximity Read ↗

Primary Hemophagocytic Lymphohistiocytosis: A Severe Immune Dysregulatory Disease with Various Genotypic Features and Outcomes: A Cross-Sectional Study from a Tertiary Pediatric CenterSemantic proximity Read ↗

Primary hemophagocytic lymphohistiocytosis in adults: the utility of family surveys in a single-center study from ChinaSemantic proximity Read ↗

Genotype characteristics and immunological indicator evaluation of 311 hemophagocytic lymphohistiocytosis cases in China.Semantic proximity Read ↗

[Association between genotype and clinical phenotype in children with primary hemophagocytic lymphohistiocytosis].Semantic proximity Read ↗

Severe adult hemophagocytic lymphohistiocytosis (HLHa) correlates with HLH-related gene variants.Semantic proximity Read ↗

Prognostic Factors and Long-term Outcomes in 41 Children With Primary Hemophagocytic Lymphohistiocytosis: Report of a Single-center Experience and Review of the Literature.Semantic proximity Read ↗

Genetic variant spectrum in 265 Chinese patients with hemophagocytic lymphohistiocytosis: Molecular analyses of PRF1, UNC13D, STX11, STXBP2, SH2D1A, and XIAP.Semantic proximity Read ↗

Molecular genetics of primary hemophagocytic lymphohistiocytosis among Polish patientsSemantic proximity Read ↗

Clinical presentation and outcome of pediatric patients with hemophagocytic lymphohistiocytosis in China: A retrospective multicenter study.Semantic proximity Read ↗

Risk factors of in-hospital death in pediatric patients with hemophagocytic lymphohistiocytosis: A case-control studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.