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Article

Clinico-laboratory profile and perforin gene mutations of pediatric hemophagocytic lymphohistiocytosis cases: a five-year single center study.

The Pan African medical journal - 1 Jan 2020

Almalky Mohamed Abdelkader, Saleh Safaa Hamdy Ahmad, Baz Eman Gamal, Fakhr Ahmed Elsadek

Abstract excerpt

INTRODUCTION: hemophagocytic lymphohistiocytosis (HLH) is an immunological disease characterized by hemophagocytosis of blood cells and proliferation of T-cells and histiocytes in the spleen and bone marrow then infiltration into body organs. Familial HLH (FHL) is a fatal disorder and determining gene mutations is a good guide for predicting the prognosis and choosing treatment options. This study aimed to...

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Identifiers

PMID: 33224420
DOI: 10.11604/pamj.2020.36.354.25079
PMCID: PMC7664152

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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