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Clinical Phenotype and Prognostic Significance of Frailty in Transthyretin Cardiac Amyloidosis

12 Mar 2025

Abstract excerpt

BACKGROUND: The prevalence and clinical impact of frailty in transthyretin cardiac amyloidosis (ATTR-CA) remains poorly characterized. OBJECTIVES: This study aimed to evaluate the prevalence, clinical determinants, and prognostic significance of frailty in a large cohort of patients with ATTR-CA. METHODS: Frailty was assessed in 880 patients with ATTR-CA (median age 80 years [Q1-Q3: 75-84 years], 719 [81.7%]...

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PMID: 40246385
DOI: 10.1016/j.jaccao.2025.01.018

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