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Article

Clinical and genetic profile of patients enrolled in the Transthyretin Amyloidosis Outcomes Survey (THAOS): 14-year update.

Orphanet journal of rare diseases - 18 Jun 2022

Dispenzieri Angela, Coelho Teresa, Conceição Isabel, Waddington-Cruz Márcia, Wixner Jonas, Kristen Arnt V, Rapezzi Claudio, Planté-Bordeneuve Violaine, Gonzalez-Moreno Juan, Maurer Mathew S, Grogan Martha, Chapman Doug, Amass Leslie

Abstract excerpt

BACKGROUND: Transthyretin amyloidosis (ATTR amyloidosis) is a rare, life-threatening disease caused by the accumulation of variant or wild-type (ATTRwt amyloidosis) transthyretin amyloid fibrils in the heart, peripheral nerves, and other tissues and organs. METHODS: Established in 2007, the Transthyretin Amyloidosis Outcomes Survey (THAOS) is the largest ongoing, global, longitudinal observational study of...

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Identifiers

PMID: 35717381
DOI: 10.1186/s13023-022-02359-w
PMCID: PMC9206752

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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