Article
The genetic architecture of cell type-specific cis regulation in maize.
Science (New York, N.Y.) - 18 Apr 2025
Marand Alexandre P, Jiang Luguang, Gomez-Cano Fabio, Minow Mark A A, Zhang Xuan, Mendieta John P, Luo Ziliang, Bang Sohyun, Yan Haidong, Meyer Cullan, Schlegel Luca, Johannes Frank, Schmitz Robert J
Abstract excerpt
Gene expression and complex phenotypes are determined by the activity of cis-regulatory elements. However, an understanding of how extant genetic variants affect cis regulation remains limited. Here, we investigated the consequences of cis-regulatory diversity using single-cell genomics of more than 0.7 million nuclei across 172 Zea mays (maize) inbreds. Our analyses pinpointed cis-regulatory elements distinct to...
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