Article
microRNAs in Type 1 Diabetes: Roles, Pathological Mechanisms, and Therapeutic Potential
2 Apr 2025
Abstract excerpt
Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by the progressive destruction of pancreatic β-cells, leading to insulin deficiency. The primary drivers of β-cell destruction in T1D involve autoimmune-mediated processes that trigger chronic inflammation and ultimately β-cell loss. Regulatory microRNAs (miRNAs) play a crucial role in modulating these processes by regulating gene expression...
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