Low-density lipoprotein cholesterol elevation, ketogenic diets, body mass index, and heterozygous ABCG5 genetic variation: Review, case report, and large population analysis.

Abstract excerpt

BACKGROUND: Low body mass index (BMI) has been associated with marked low-density-lipoprotein-cholesterol (LDL-C) elevations in response to very-low-carbohydrate diets (VLCD). METHODS: We report a case (51-year-old woman, BMI 18.5 kg/m2) whose LDL-C was >500 mg/dL on a VLCD. We characterized her plasma lipoproteins and noncholesterol-sterols (gas chromatography/mass spectrometry) and the DNA sequences of her...

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