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ESCRT may function as a tumor biomarker, transitioning from pan-cancer analysis to validation within breast cancer

31 Mar 2025

Abstract excerpt

Background Studies have shown that ESCRT genes affect cell aging, immune environment, and tumors. BRCA was used to explore its effects on tumor prognosis and therapy. Methods The data sets of Cancer Genome Atlas (TCGA), Genome-Tissue Expression Plan (GTEX), Human Protein Mapping (HPA), Gene Expression Omnibus (GEO), Clinical Proteomic Tumor Analysis Consortium (CPTAC), R software package, and bioinformatics...

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PMID: 40230849
DOI: 10.3389/fimmu.2025.1531940

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