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Article

Mendelian randomization study of causal link from gut microbiota to colorectal cancer.

BMC cancer - 30 Dec 2022

Ni Jing-Jing, Li Xiao-Song, Zhang Hong, Xu Qian, Wei Xin-Tong, Feng Gui-Juan, Zhao Min, Zhang Zi-Jia, Zhang Lei, Shen Gen-Hai, Li Bin

Abstract excerpt

Recent studies have shown the relevance of gut microbiota in the occurrence and development of colorectal cancer (CRC), but the causal relationship remains unclear in the human population. The present study aims to assess the causal relationship from the gut microbiota to CRC and to identify specific causal microbe taxa via genome-wide association study (GWAS) summary statistics based two-sample Mendelian...

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Identifiers

PMID: 36585646
DOI: 10.1186/s12885-022-10483-w
PMCID: PMC9804960

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