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Genetics, diet, microbiota, and metabolome: partners in crime for colon carcinogenesis

29 Oct 2024

Abstract excerpt

Colorectal cancer (CRC) ranks among the most prevalent malignant tumors worldwide, with a multifactorial etiology encompassing genetic, environmental, and life-style factors, as well as the intestinal microbiota and its metabolome. These risk factors often work together in specific groups of patients, influencing how CRC develops and progresses. Importantly, alterations in the gut microbiota act as a critical...

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PMID: 39470880
DOI: 10.1007/s10238-024-01505-x

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