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Article

BRAF V600E Mutation in Ganglioglioma: Impact on Epileptogenicity and Implications for Surgical Strategy.

European journal of neurology - 1 Apr 2025

Tomschik Matthias, Horner Eva, Lang Alexandra, Mayer Florian, Czech Thomas, Kasprian Gregor, Pataraia Ekaterina, Azizi Amedeo A, Feucht Martha, Rössler Karl, Haberler Christine, Dorfer Christian

Abstract excerpt

OBJECTIVE: Gangliogliomas are commonly found pathologies in patients undergoing epilepsy surgery. While resections can be curative, seizure relapses occur. Expression of CD34 and the BRAF V600E mutation are the most common molecular biomarkers found in gangliogliomas, but their influence on seizure outcomes is unclear. We therefore reviewed our experience over two decades to better describe prognostic factors....

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Share to Antigens, CD34
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Child, Preschool

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Share to Proto-Oncogene Proteins B-raf

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Source

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Identifiers

PMID: 40186496
DOI: 10.1111/ene.70136
PMCID: PMC11971660

Genes

BRAF
CD34

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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