Genomic profiling of aggressive pathologic features in lung adenocarcinoma.

Abstract excerpt

INTRODUCTION: Pathologic features involving LVI (lympho-vascular invasion), PNI (perineural invasion), STAS (spread through air spaces), and Grade 3 pattern (from the International Association for the Study of Lung Cancer grading system) are related to having an aggressive phenotype and linked to poor prognosis. However, few studies have conducted in-depth analyses of these features simultaneously with genomic...

Topics

• Humans
• Lung Neoplasms
• Male
• Female
• Mutation
• Middle Aged
• Adenocarcinoma of Lung