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Network pharmacology and in silico analysis reveal Kochiae Fructus as a potential therapeutic against atopic dermatitis through immunomodulatory pathway interactions

3 Apr 2025

Abstract excerpt

Atopic dermatitis (AD), a chronic inflammatory disorder, poses significant therapeutic challenges owing to its complex pathophysiology, involving disrupted epidermal barrier function and immune dysregulation. This study investigated the therapeutic potential of Kochiae Fructus in AD treatment using bioinformatics, including network pharmacology and molecular docking techniques. We identified 19 key phytochemicals...

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PMID: 40179089
DOI: 10.1371/journal.pone.0320818

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