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Article

Social and Behavioral Genomics: On the Ethics of the Research and Its Downstream Applications.

Annual review of genomics and human genetics - 1 Aug 2025

Martschenko Daphne Oluwaseun, Lee Sandra Soo-Jin, Meyer Michelle N, Parens Erik

Abstract excerpt

Social and behavioral scientists increasingly work with geneticists or adapt the methods of genetic research to investigate genomic variation in a wide variety of behavioral and social phenotypes. Using genome-wide association studies, these social and behavioral genomics (SBG) researchers generate polygenic indexes (PGIs)-weighted sums of the estimated effects of each genetic variant on an individual's...

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PMID: 40169009
DOI: 10.1146/annurev-genom-011224-015733
PMCID: PMC12551439

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