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Article

PD-L1 gene variants as predictors of recurrent pregnancy loss: A case-control study among Kazakh women in Central and West Kazakhstan.

Journal of reproductive immunology - 1 Jun 2025

Almawi Wassim Y, Aimagambetova Gulzhanat, Tursunov Abay, Turesheva Akbayan, Marat Aizada, Ilmaliyeva Aktoty, Atageldiyeva Kuralay

Abstract excerpt

Emerging evidence implicates immune dysfunction in maintaining maternal-fetal tolerance, particularly the programmed death-ligand 1 (PD-L1) pathway. The association between PD-L1 gene variants and recurrent pregnancy loss (RPL) in women from Central and West Kazakhstan was investigated, and correlations between PD-L1 genotypes and demographic or clinical features were explored. This case-control study included...

Read the complete abstract on PubMed

Topics

Humans
Female
Kazakhstan
Abortion, Habitual
Adult
Pregnancy

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Case-Control Studies

Polymorphism, Single Nucleotide

B7-H1 Antigen

Genetic Predisposition to Disease

Genotype

Source

Identifiers

PMID: 40154136
DOI: 10.1016/j.jri.2025.104524

Provenance

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