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Article

Loss of Atoh8 Affects Neurocranial and Axial Skeleton Development in Zebrafish.

Frontiers in bioscience (Landmark edition) - 5 Mar 2025

Fragale Ninfa, Divvela Satya Srirama Karthik, Williams-Ward Victoria Clare, Brand-Saberi Beate

Abstract excerpt

BACKGROUND: The basic helix-loop-helix (bHLH) transcription factor atonal homologue 8 (Atoh8) has been implicated in various developmental and physiological processes by means of transient knockdown and conditional knockout approaches in zebrafish, chick and mouse. Despite its demonstrated involvement in multiple tissues, the role of Atoh8 remains elusive in zebrafish. A recent permanent knockout study in...

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PMID: 40152384
DOI: 10.31083/FBL26806

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