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A virus-encoded microRNA contributes to evade innate immune response during SARS-CoV-2 infection

2021-09-09

Abstract excerpt

SARS-CoV-2 infection results in impaired interferon response in severe COVID-19 patients. However, how SARS-CoV-2 interferes with host immune response is incompletely understood. Here, we sequenced small RNAs from SARS-CoV-2-infected human cells and identified a micro-RNA (miRNA) encoded in a recently evolved region of the viral genome. We show that the virus-encoded miRNA produces two miRNA isoforms in infected c...

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Identifiers and source

Literature Corpus work
98cb6062-5264-50e4-a4be-7c601a9ead50
DOI
10.1101/2021.09.09.459577
Open publication

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A virus-encoded microRNA contributes to evade innate immune response during SARS-CoV-2 infectionDOI 10.1101/2021.09.09.459577
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