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Semaphorin 7a Regulates the Expression of IL ‐4 and IL ‐33 in a Cell Model of Atopic Dermatitis and Is Associated With Disease Severity

1 Mar 2025

Abstract excerpt

Neuroimmune interaction is crucial to inducing pruritic sensations in atopic dermatitis (AD). In this study, we examine the neuroimmune pathways involved in children with AD. HumanMethylation450 BeadChip and GeneChip Human Transcriptome Array 2.0 from 24 children with ad and 24 healthy controls were cross-referenced with gene expression data from GSE116486. SEMA7A, which encodes for semaphorin 7a and is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40129061
DOI: 10.1111/exd.70087

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