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SIP2 is the master transcription factor of Plasmodium merozoite formation

21 Mar 2025

Abstract excerpt

Malaria, one of the most serious infectious diseases worldwide, is caused by the proliferation of Plasmodium parasites through repeated cycles of intraerythrocytic development. The parasite replicates via schizogony in host erythrocytes, producing multiple progeny merozoites that invade new erythrocytes. Although merozoite formation is the most crucial step in malaria pathogenesis, its molecular mechanism remains...

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PMID: 40117352
DOI: 10.1126/sciadv.ads5458

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