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Article

Genetic variants in QRICH2 gene among Jordanians with sperm motility disorders.

The Libyan journal of medicine - 1 Dec 2025

Alhnaity Haneen M, Shraim Ala'a S, Abumsimir Berjas, Hattab Dima, Ghazzy Asma M, Abdelhalim May, Abdel Majeed Bayan A, Daoud Enas, Jarrar Yazun

Abstract excerpt

Sperm motility, a key determinant of male fertility, is often impaired by genetic variations affecting flagellar formation. The glutamine-rich protein 2 (QRICH2) gene encodes a protein essential for sperm flagella biogenesis and structural integrity. This study investigates genetic variations within exon 3 of the QRICH2 gene, identifying novel heterozygous variants associated with sperm tail-specific...

Read the complete abstract on PubMed

Topics

Humans
Male
Jordan
Sperm Motility
Polymorphism, Single Nucleotide
Asthenozoospermia

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Adult

Sperm Tail

Infertility, Male

Source

Open in PubMed Open full text

Identifiers

PMID: 40107860
DOI: 10.1080/19932820.2025.2481741
PMCID: PMC11924270

Genes

QRICH2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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