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Comprehensive detection of pathogens in immunocompromised children with bloodstream infections by next-generation sequencing

22 Feb 2018

Abstract excerpt

Bloodstream infection (BSI) is a severe complication in immunocompromised patients. Next-generation sequencing (NGS) allows us to analyze comprehensively and quantitatively all microorganisms present in a clinical sample. Thirty-five pediatric patients (12 with BSI and 23 with suspected BSI/negative blood culture) were enrolled. Plasma/serum samples were used for sequencing and the results were compared with...

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PMID: 29491477
DOI: 10.1038/s41598-018-22133-y

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