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Low HDL concentration in rs2048327-G carriers can predispose men to develop coronary heart disease: Tehran Cardiometabolic genetic study (TCGS).

Gene - 30 Apr 2021

Najd Hassan Bonab Leila, Moazzam-Jazi Maryam, Miri Moosavi Reyhaneh-Sadat, Fallah Mohammad-Sadegh, Lanjanian Hossein, Masjoudi Sajedeh, Daneshpour Maryam S

Abstract excerpt

Recent genome-wide association studies (GWAS) highlighted the importance of genetic variations on SLC22A3 and MIA3 genes in developing coronary heart disease (CHD) among different ethnicities. However, the influence of these variations is not recognized within the Iranian population. Hence, in the present study, we aim to investigate two key single nucleotide polymorphisms (SNPs) on CHD incidence in this...

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PMID: 33581269
DOI: 10.1016/j.gene.2021.145485

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