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Article

Association of m.5178C>A variant with serum lipid levels: a systematic review and meta-analysis.

Bioscience reports - 22 Dec 2021

Liu Fuqiang, He Jiyun, Wang Shengping, Yu Feng, Luo Zhi

Abstract excerpt

BACKGROUND: Emerging evidence shows that m.5178C>A variant is associated with a lower risk of coronary artery disease (CAD). However, the specific mechanisms remain elusive. Since dyslipidemia is one of the most critical risk factors for CAD and accounts for at least 50% of the population-attributable risk, it is tempting to speculate that the reduced CAD risk caused by the m.5178C>A variant may stem from an...

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Identifiers

PMID: 34859818
DOI: 10.1042/BSR20212246
PMCID: PMC8685646

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