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Harnessing Computational Strategies to Overcome Challenges in mRNA Vaccines

10 Mar 2025

Abstract excerpt

In recent years, the introduction of mRNA vaccines for SARS-CoV2 and respiratory syncytial virus (RSV) has highlighted the success of the mRNA technology platform. Designing mRNA sequences involves multiple components and requires balancing several parameters, including enhancing transcriptional efficiency, boosting antigenicity, and minimizing immunogenicity. Moreover, changes in the composition and properties...

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PMID: 40062918
DOI: 10.1152/physiol.00047.2024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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