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Article

Prevalence and cardiac risk of familial ST depression syndrome: A study of 12 million electrocardiograms.

Heart rhythm - 1 Feb 2026

Frosted Rasmus, Sørensen Kathrine Kold, Andersen Mikkel Porsborg, Polcwiartek Christoffer, Zheng Chaoqun, Christensen Helle Collatz, Kragholm Kristian Hay, Graff Claus, Torp-Pedersen Christian, Christensen Alex Hørby

Abstract excerpt

BACKGROUND: Familial ST depression syndrome (Fam-STD) is a recently identified inherited cardiac disease characterized by a distinct electrocardiographic phenotype and occurrence of arrhythmias and heart failure. OBJECTIVE: We aimed to investigate the electrocardiographic prevalence of the Fam-STD and its association with cardiac events in a large, nationwide cohort. METHODS: We used a Danish nationwide...

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PMID: 40049379
DOI: 10.1016/j.hrthm.2025.02.048

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