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Associations of Maternal Smoking During Pregnancy and Genetic Susceptibility with Incident Asthma from a Cohort Study.

Prevention science : the official journal of the Society for Prevention Research - 1 Apr 2025

Zhang Shuo, Wang Ting, Zeng Ping

Abstract excerpt

Maternal smoking during pregnancy exhibited an adverse influence on asthma, but its joint effect with genetic factors remained elusive. Moreover, whether there existed a moderating role of genetic susceptibility in this effect on childhood/adolescent-onset asthma (COA) and adult-out asthma (AOA) was unknown. We employed the UK Biobank cohort to estimate the effect of maternal smoking during pregnancy on the risk...

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Asthma
Child
Cohort Studies
Pregnancy
Prenatal Exposure Delayed Effects

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PMID: 40045075
DOI: 10.1007/s11121-025-01793-z

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