Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of Mitochondrial Deterioration in Physiological and Pathological Brain Aging

1 Jan 2004

Abstract excerpt

BACKGROUND: Mitochondria are widely reported to occupy a unique role in modulating cell viability, senescence and death. This is consistently supported by the multiple functions of these organelles. In addition to providing the energy for the myriad of cellular performances, mitochondria are involved in regulating thermogenesis, calcium buffering, integration of pro- and anti-apoptotic signals. OBJECTIVE: To...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to GDF15 and Related Biomarkers
Share to Genetics, Aging, and Longevity in Model Organisms
Share to Mitochondrial Function and Pathology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15114042
DOI: 10.1159/000076779

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of Mitochondrial Deterioration in Physiological and Pathological Brain AgingPMID 15114042Read ↗

Mitochondrial Dysfunction: A Key Player in Brain Aging and DiseasesSemantic proximity Read ↗

Mitochondrial turnover and homeostasis in ageing and neurodegenerationSemantic proximity Read ↗

Mitochondrial dysfunction and its association with age-related disordersSemantic proximity Read ↗

Novel therapeutic strategies targeting mitochondria as a gateway in neurodegenerationSemantic proximity Read ↗

Targeting Mitochondria to Control Ageing and SenescenceSemantic proximity Read ↗

The Mitochondrial Basis of Aging and Age-Related DisordersSemantic proximity Read ↗

Mitochondrial Dysfunction: a Notable Contributor to the Progression of Alzheimer’s & Parkinson’s DiseaseSemantic proximity Read ↗

Mitochondria in aging and age-associated diseasesSemantic proximity Read ↗

Mitochondrial respiratory chain dysfunction: implications in neurodegeneration.Semantic proximity Read ↗

Reconsidering the Role of Mitochondria in AgingSemantic proximity Read ↗

Mitophagy plays a central role in mitochondrial ageingSemantic proximity Read ↗

Mitochondrial Dysfunctions: A Red Thread across Neurodegenerative DiseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.