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A novel mechanism of FTO modulating the progression of endometriosis through mediating the m6A methylation of GEF-H1 in a YTHDF1-dependent manner

25 Feb 2025

Abstract excerpt

BACKGROUND: Endometriosis (EMs) is a condition characterized by the growth of endometrial tissue outside the uterine cavity. Although this condition is benign, it has cancer-like features. N6-methyladenosine (m6A) is a common RNA modification involved in diverse biological processes, but its role in EMs remains unclear. METHODS: A human endometrial stromal cell line (HESCs), primary eutopic endometrial stromal...

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PMID: 40000966
DOI: 10.1186/s10020-025-01130-8

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