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The involvement of RNA N6‐methyladenosine and histone methylation modification in decidualization and endometriosis‐associated infertility

1 Feb 2024

Abstract excerpt

Abstract Defective decidualization of endometrial stromal cells (ESCs) in endometriosis (EM) patients leads to inadequate endometrial receptivity and EM‐associated infertility. Hypoxia is an inevitable pathological process of EM and participates in deficient decidualization of the eutopic secretory endometrium. Enhancer of zeste homology 2 (EZH2) is a methyltransferase which catalyses H3K27Me3, leading to...

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PMID: 38344897
DOI: 10.1002/ctm2.1564

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The involvement of RNA N6‐methyladenosine and histone methylation modification in decidualization and endometriosis‐associated infertilityPMID 38344897Read ↗

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A novel mechanism of FTO modulating the progression of endometriosis through mediating the m6A methylation of GEF-H1 in a YTHDF1-dependent mannerSemantic proximity Read ↗

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Programmed downregulation of METTL3 is essential for decidualization in both humans and miceSemantic proximity Read ↗

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