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Seasonal Influences on Human Placental Transcriptomes Associated with Spontaneous Preterm Birth

18 Feb 2025

Abstract excerpt

Demographic studies have revealed a strong association between exposure to high ambient temperatures during pregnancy and increased risks of preterm birth (PTB). The mechanism underlying this association is unclear, but it is plausible that altered placental function may contribute to it. In this study, we conducted differential gene expression analysis, gene set enrichment analysis (GSEA), and gene ontology (GO)...

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PMID: 39996774
DOI: 10.3390/cells14040303

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